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Uracil incorporation: A source of pulse-labeled DNA fragments in the replication of the Escherichia coli chromosome

Uracil is incorporated into newly synthesized DNA by mutants of Escherichia coli with reduced levels of dUTPase (dUTP nucleotidohydrolase; EC 3.6.1.23). Excision-repair of the incorporated uracil results in the generation of labeled DNA fragments that appear after brief pulses with [(3)H]thymidine [...

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Autores principales: Tye, Bik-Kwoon, Chien, Janice, Lehman, I. R., Duncan, Bruce K., Warner, Huber R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1978
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC411220/
https://ncbi.nlm.nih.gov/pubmed/203931
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