Uracil incorporation: A source of pulse-labeled DNA fragments in the replication of the Escherichia coli chromosome

Uracil is incorporated into newly synthesized DNA by mutants of Escherichia coli with reduced levels of dUTPase (dUTP nucleotidohydrolase; EC 3.6.1.23). Excision-repair of the incorporated uracil results in the generation of labeled DNA fragments that appear after brief pulses with [(3)H]thymidine [...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Tye, Bik-Kwoon, Chien, Janice, Lehman, I. R., Duncan, Bruce K., Warner, Huber R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1978
Soggetti:	Biological Sciences: Biochemistry
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/203931/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.233
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