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The Emerging Era of Genomic Data Integration for Analyzing Splice Isoform Function

The vast majority of multi-exon genes in humans undergo alternative splicing, which greatly increases the functional diversity of protein species. Predicting functions at the isoform level is essential to further our understanding of developmental abnormalities and cancers, which frequently exhibit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Hong-Dong, Menon, Rajasree, Omenn, Gilbert S., Guan, Yuanfang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112133/
https://ncbi.nlm.nih.gov/pubmed/24951248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2014.05.005
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