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Shape Readout of AT Rich DNA by Carbohydrates

Gene expression can be altered by small molecules that target DNA; sequence as well as shape selectivities are both extremely important for DNA recognition by intercalating and groove-binding ligands. We have characterized a carbohydrate scaffold (1) exhibiting DNA “shape readout” properties. Thermo...

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Detalhes bibliográficos
Main Authors: Kumar, Sunil, Spano, Meredith Newby, Arya, Dev P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112085/
https://ncbi.nlm.nih.gov/pubmed/24281844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22448
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