Direct imaging of RecA nucleation and growth on single molecules of SSB-coated ssDNA

Escherichia coli RecA is the defining member of a ubiquitous class of DNA strand exchange proteins that are essential for homologous recombination, a pathway that maintains genomic integrity by repairing broken DNA(1). To function, filaments of RecA must nucleate and grow on single-stranded DNA (ssD...

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Bibliografiska uppgifter
Huvudupphovsmän: Bell, Jason C., Plank, Jody L., Dombrowski, Christopher C., Kowalczykowski, Stephen C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112059/
https://ncbi.nlm.nih.gov/pubmed/23103864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11598
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