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Tumor associated fibroblasts enhance head and neck squamous cell carcinoma proliferation, invasion, and metastasis in preclinical models

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) has had little improvement in mortality rates in decades. A clearer understanding of the HNSCC tumor microenvironment will aid in finding more effective targeted therapies for this disease. Tumor associated fibroblasts (TAFs) are the largest...

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Main Authors: Wheeler, Sarah Elizabeth, Shi, Huifang, Lin, Fangchen, Dasari, Sumana, Bednash, Joseph, Thorne, Stephen, Watkins, Simon, Joshi, Radhika, Thomas, Sufi Mary
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111913/
https://ncbi.nlm.nih.gov/pubmed/23728942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.23312
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