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Abnormal cellular localization of thyroglobulin mRNA associated with hereditary congenital goiter and thyroglobulin deficiency.

The goiters in a breed of hypothyroid goats contain only minute amounts of thyroblobulin-related antigens (0.01% of normal value). We have analyzed these goiters for the presence of mRNA coding for thyroglobulin. Using DNA complementary to beef 33S thyroglobulin mRNA as a probe, we found that the mR...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Van Voorthuizen, W F, Dinsart, C, Flavell, R A, DeVijlder, J J, Vassart, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1978
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411186/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/272675/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.74
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