Twice-Daily Subcutaneous Injection of Kisspeptin-54 Does Not Abolish Menstrual Cyclicity in Healthy Female Volunteers

BACKGROUND: Kisspeptin is a critical hypothalamic regulator of reproductive function. Chronic kisspeptin administration causes profound tachyphylaxis in male monkeys and in women with functional hypothalamic amenorrhea. The pharmacological effects of chronic kisspeptin exposure in healthy women with...

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Detalhes bibliográficos
Main Authors: Jayasena, C. N., Comninos, A. N., Nijher, G. M. K., Abbara, A., De Silva, A., Veldhuis, J. D., Ratnasabapathy, R., Izzi-Engbeaya, C., Lim, A., Patel, D. A., Ghatei, M. A., Bloom, S. R., Dhillo, W. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Endocrine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111853/
https://ncbi.nlm.nih.gov/pubmed/24030945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-1069
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