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Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to coordination defects in mice
Selenocysteine Insertion Sequence (SECIS)-Binding Protein 2 (Secisbp2) binds to SECIS elements located in the 3′-untranslated region of eukaryotic selenoprotein mRNAs. It facilitates incorporation of the rare amino acid selenocysteine in response to UGA codons. Inactivation of Secisbp2 in hepatocyte...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4111790/ https://ncbi.nlm.nih.gov/pubmed/24844465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140423 |
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