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Doxorubicin enhances Snail/LSD1-mediated PTEN suppression in a PARP1-dependent manner

The transcription factor Snail not only functions as a master regulator of epithelial–mesenchymal transition (EMT), but also mediates cell proliferation and survival. While previous studies have showed that Snail protects tumor cells from apoptosis through transcriptional repression of PTEN, the spe...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lin, Yiwei, Kang, Tiebang, Zhou, Binhua P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111717/
https://ncbi.nlm.nih.gov/pubmed/24675890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28619
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