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The other side of the coin: The tumor-suppressive aspect of oncogenes and the oncogenic aspect of tumor-suppressive genes, such as those along the CCND–CDK4/6–RB axis

Although cancer-regulatory genes are dichotomized to oncogenes and tumor-suppressor gene s, in reality they can be oncogenic in one situation but tumor-suppressive in another. This dual-function nature, which sometimes hampers our understanding of tumor biology, has several manifestations: (1) Most...

詳細記述

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書誌詳細
主要な著者: Lou, Xiaomin, Zhang, Ju, Liu, Siqi, Xu, Ningzhi, Liao, D Joshua
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111714/
https://ncbi.nlm.nih.gov/pubmed/24799665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29082
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