Energy conformation study of Met-enkephalin and its D-Ala2 analogue and their resemblance to rigid opiates.
Conformational similarities of Met-enkephalin and its D-Ala2 analogue to rigid opiates were studied by both empirical and quantum mechanical methods. By both methods, conformers with maximum resemblance to rigid opiates have the highest energies. Conformers with the lowest energy had no resemblance...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1978
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411171/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/272674/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.7 |
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