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Mta2 promotes Tipin-dependent maintenance of replication fork integrity
Orderly progression of S phase requires the action of replisome-associated Tipin and Tim1 proteins, whose molecular function is poorly understood. Here, we show that Tipin deficiency leads to the accumulation of aberrant replication intermediates known as reversed forks. We identified Mta2, a subuni...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4111703/ https://ncbi.nlm.nih.gov/pubmed/24830473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29157 |
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