Cockayne syndrome protein A is a transcription factor of RNA polymerase I and stimulates ribosomal biogenesis and growth

Mutations in the Cockayne syndrome A (CSA) protein account for 20% of Cockayne syndrome (CS) cases, a childhood disorder of premature aging and early death. Hitherto, CSA has exclusively been described as DNA repair factor of the transcription-coupled branch of nucleotide excision repair. Here we sh...

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Bibliographic Details
Main Authors: Koch, Sylvia, Garcia Gonzalez, Omar, Assfalg, Robin, Schelling, Adrian, Schäfer, Patrick, Scharffetter-Kochanek, Karin, Iben, Sebastian
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111694/
https://ncbi.nlm.nih.gov/pubmed/24781187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29018
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