Dexamethasone-induced autophagy mediates muscle atrophy through mitochondrial clearance

Glucocorticoids, such as dexamethasone, enhance protein breakdown via ubiquitin–proteasome system. However, the role of autophagy in organelle and protein turnover in the glucocorticoid-dependent atrophy program remains unknown. Here, we show that dexamethasone stimulates an early activation of auto...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Troncoso, Rodrigo, Paredes, Felipe, Parra, Valentina, Gatica, Damián, Vásquez-Trincado, César, Quiroga, Clara, Bravo-Sagua, Roberto, López-Crisosto, Camila, Rodriguez, Andrea E, Oyarzún, Alejandra P, Kroemer, Guido, Lavandero, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111682/
https://ncbi.nlm.nih.gov/pubmed/24897381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29272
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados