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Rac1-dependent recruitment of PAK2 to G(2) phase centrosomes and their roles in the regulation of mitotic entry
During mitotic entry, the centrosomes provide a scaffold for initial activation of the CyclinB/Cdk1 complex, the mitotic kinase Aurora A, and the Aurora A-activating kinase p21-activated kinase (PAK). The activation of PAK at the centrosomes is yet regarded to happen independently of the Rho-GTPases...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4111676/ https://ncbi.nlm.nih.gov/pubmed/24840740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29279 |
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