Actin Cytoskeletal Disruption following Cryopreservation Alters the Biodistribution of Human Mesenchymal Stromal Cells In Vivo

Mesenchymal stromal cells have shown clinical promise; however, variations in treatment responses are an ongoing concern. We previously demonstrated that MSCs are functionally stunned after thawing. Here, we investigated whether this cryopreservation/thawing defect also impacts the postinfusion biod...

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Detalhes bibliográficos
Main Authors: Chinnadurai, Raghavan, Garcia, Marco A., Sakurai, Yumiko, Lam, Wilbur A., Kirk, Allan D., Galipeau, Jacques, Copland, Ian B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110775/
https://ncbi.nlm.nih.gov/pubmed/25068122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.05.003
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