Association between the number of coadministered P-glycoprotein inhibitors and serum digoxin levels in patients on therapeutic drug monitoring

BACKGROUND: The ABC transporter P-glycoprotein (P-gp) is recognized as a site for drug-drug interactions and provides a mechanistic explanation for clinically relevant pharmacokinetic interactions with digoxin. The question of whether several P-gp inhibitors may have additive effects has not yet bee...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Englund, Gunilla, Hallberg, Pär, Artursson, Per, Michaëlsson, Karl, Melhus, Håkan
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2004
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC411066/
https://ncbi.nlm.nih.gov/pubmed/15061868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-2-8
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk