Novel Cartilage Oligomeric Matrix Protein (COMP) Neoepitopes Identified in Synovial Fluids from Patients with Joint Diseases Using Affinity Chromatography and Mass Spectrometry

To identify patients at risk for progressive joint damage, there is a need for early diagnostic tools to detect molecular events leading to cartilage destruction. Isolation and characterization of distinct cartilage oligomeric matrix protein (COMP) fragments derived from cartilage and released into...

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Detalhes bibliográficos
Main Authors: Åhrman, Emma, Lorenzo, Pilar, Holmgren, Kristin, Grodzinsky, Alan J., Dahlberg, Leif E., Saxne, Tore, Heinegård, Dick, Önnerfjord, Patrik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110297/
https://ncbi.nlm.nih.gov/pubmed/24917676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554683
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