Proteomic Analysis of Tendon Extracellular Matrix Reveals Disease Stage-specific Fragmentation and Differential Cleavage of COMP (Cartilage Oligomeric Matrix Protein)

During inflammatory processes the extracellular matrix (ECM) is extensively remodeled, and many of the constituent components are released as proteolytically cleaved fragments. These degradative processes are better documented for inflammatory joint diseases than tendinopathy even though the pathoge...

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Detalhes bibliográficos
Main Authors: Dakin, Stephanie Georgina, Smith, Roger Kenneth Whealands, Heinegård, Dick, Önnerfjord, Patrik, Khabut, Areej, Dudhia, Jayesh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931053/
https://ncbi.nlm.nih.gov/pubmed/24398684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511972
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