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Mammalian COPII Coat Component SEC24C Is Required for Embryonic Development in Mice

COPII-coated vesicles mediate the transport of newly synthesized proteins from the endoplasmic reticulum to the Golgi. SEC24 is the COPII component primarily responsible for recruitment of protein cargoes into nascent vesicles. There are four Sec24 paralogs in mammals, with mice deficient in SEC24A,...

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Bibliografiske detaljer
Main Authors: Adams, Elizabeth J., Chen, Xiao-Wei, O'Shea, K. Sue, Ginsburg, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110293/
https://ncbi.nlm.nih.gov/pubmed/24876386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.566687
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