KRAS and YAP1 converge to regulate EMT and tumor survival

Cancer cells that express oncogenic alleles of RAS typically require sustained expression of the mutant allele for survival, but the molecular basis of this oncogene dependency remains incompletely understood. To identify genes that can functionally substitute for oncogenic RAS, we systematically ex...

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Detalhes bibliográficos
Main Authors: Shao, Diane D., Xue, Wen, Krall, Elsa B., Bhutkar, Arjun, Piccioni, Federica, Wang, Xiaoxing, Schinzel, Anna C., Sood, Sabina, Rosenbluh, Joseph, Kim, Jong W., Zwang, Yaara, Roberts, Thomas M., Root, David E., Jacks, Tyler, Hahn, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110062/
https://ncbi.nlm.nih.gov/pubmed/24954536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.004
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