Mung Bean Nuclease Treatment Increases Capture Specificity of Microdroplet-PCR Based Targeted DNA Enrichment

Targeted DNA enrichment coupled with next generation sequencing has been increasingly used for interrogation of select sub-genomic regions at high depth of coverage in a cost effective manner. Specificity measured by on-target efficiency is a key performance metric for target enrichment. Non-specifi...

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Bibliografiska uppgifter
Huvudupphovsmän: Yu, Zhenming, Cao, Kajia, Tischler, Tanya, Stolle, Catherine A., Santani, Avni B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110027/
https://ncbi.nlm.nih.gov/pubmed/25058678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103491
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