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Immunization of Mice with Lentiviral Vectors Targeted to MHC Class II+ Cells Is Due to Preferential Transduction of Dendritic Cells In Vivo

Gene transfer vectors such as lentiviral vectors offer versatile possibilities to express transgenic antigens for vaccination purposes. However, viral vaccines leading to broad transduction and transgene expression in vivo, are undesirable. Therefore, strategies capable of directing gene transfer on...

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Detalhes bibliográficos
Main Authors: Ciré, Séverine, Da Rocha, Sylvie, Yao, Roseline, Fisson, Sylvain, Buchholz, Christian J., Collins, Mary K., Galy, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109917/
https://ncbi.nlm.nih.gov/pubmed/25058148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101644
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