Exhaustive search of the SNP-SNP interactome identifies epistatic effects on brain volume in two cohorts

The SNP-SNP interactome has rarely been explored in the context of neuroimaging genetics mainly due to the complexity of conducting ∼10(11) pairwise statistical tests. However, recent advances in machine learning, specifically the iterative sure independence screening (SIS) method, have enabled the...

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Autores principales: Hibar, Derrek P., Stein, Jason L., Jahanshad, Neda, Kohannim, Omid, Toga, Arthur W., McMahon, Katie L., de Zubicaray, Greig I., Montgomery, Grant W., Martin, Nicholas G., Wright, Margaret J., Weiner, Michael W., Thompson, Paul M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109883/
https://ncbi.nlm.nih.gov/pubmed/24505811
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