Discovery and Replication of Gene Influences on Brain Structure Using LASSO Regression

We implemented least absolute shrinkage and selection operator (LASSO) regression to evaluate gene effects in genome-wide association studies (GWAS) of brain images, using an MRI-derived temporal lobe volume measure from 729 subjects scanned as part of the Alzheimer’s Disease Neuroimaging Initiative...

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主要な著者: Kohannim, Omid, Hibar, Derrek P., Stein, Jason L., Jahanshad, Neda, Hua, Xue, Rajagopalan, Priya, Toga, Arthur W., Jack, Clifford R., Weiner, Michael W., de Zubicaray, Greig I., McMahon, Katie L., Hansell, Narelle K., Martin, Nicholas G., Wright, Margaret J., Thompson, Paul M.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Research Foundation 2012
主題:
Neuroscience
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412288/
https://ncbi.nlm.nih.gov/pubmed/22888310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2012.00115
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