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Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate
Sphingosine-1-phosphate (S1P) mediates several cytoprotective functions of HDL. apoM acts as a S1P binding protein in HDL. Erythrocytes are the major source of S1P in plasma. After glomerular filtration, apoM is endocytosed in the proximal renal tubules. Human or murine HDL elicited time- and dose-d...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Biochemistry and Molecular Biology
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4109767/ https://ncbi.nlm.nih.gov/pubmed/24950692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M050021 |
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