Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans

While genetic determinants strongly influence HDL cholesterol (HDLc) levels, most genetic causes underlying variation in HDLc remain unknown. We aimed to identify novel rare mutations with large effects in candidate genes contributing to extreme HDLc in humans, utilizing family-based Mendelian genet...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Singaraja, Roshni R., Tietjen, Ian, Hovingh, G. Kees, Franchini, Patrick L., Radomski, Chris, Wong, Kenny, vanHeek, Margaret, Stylianou, Ioannis M., Lin, Linus, Wang, Liangsu, Mitnaul, Lyndon, Hubbard, Brian, Winther, Michael, Mattice, Maryanne, Legendre, Annick, Sherrington, Robin, Kastelein, John J., Akinsanya, Karen, Plump, Andrew, Hayden, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2014
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109763/
https://ncbi.nlm.nih.gov/pubmed/24891332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M048710
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker