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Cutis Laxa: Intersection of Elastic Fiber Biogenesis, TGFβ Signaling, the Secretory Pathway and Metabolism

Cutis laxa (CL), a disease characterized by redundant and inelastic skin, displays extensive locus heterogeneity. Together with geroderma osteodysplasticum and arterial tortuosity syndrome, which show phenotypic overlap with CL, eleven CL-related genes have been identified to date, which encode prot...

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Bibliografiske detaljer
Main Authors: Urban, Zsolt, Davis, Elaine C.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109627/
https://ncbi.nlm.nih.gov/pubmed/23954411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2013.07.006
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