Multi-electrode array study of neuronal cultures expressing nicotinic β2-V287L subunits, linked to autosomal dominant nocturnal frontal lobe epilepsy. An in vitro model of spontaneous epilepsy

Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is a partial sleep-related epilepsy which can be caused by mutant neuronal nicotinic acetylcholine receptors (nAChR). We applied multi-electrode array (MEA) recording methods to study the spontaneous firing activity of neocortical cultures...

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Autores principales: Gullo, Francesca, Manfredi, Irene, Lecchi, Marzia, Casari, Giorgio, Wanke, Enzo, Becchetti, Andrea
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109561/
https://ncbi.nlm.nih.gov/pubmed/25104926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncir.2014.00087
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