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The cystine/glutamate antiporter: when too much of a good thing goes bad

Glutamate excitotoxicity represents a major cellular component of ischemic brain injury. In this issue of the JCI, Soria and colleagues reveal that the cystine/glutamate exchanger is an important source of excitotoxic glutamate in response to ischemia induced by oxygen and glucose deprivation. As th...

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Библиографические подробности
Главный автор: Reissner, Kathryn J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109541/
https://ncbi.nlm.nih.gov/pubmed/25036700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76627
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