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The cystine/glutamate antiporter: when too much of a good thing goes bad
Glutamate excitotoxicity represents a major cellular component of ischemic brain injury. In this issue of the JCI, Soria and colleagues reveal that the cystine/glutamate exchanger is an important source of excitotoxic glutamate in response to ischemia induced by oxygen and glucose deprivation. As th...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4109541/ https://ncbi.nlm.nih.gov/pubmed/25036700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76627 |
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