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Mitosis: Too Much of a Good Thing (Can Be Bad)

Recent studies reveal that the precise regulation of microtubule dynamics is essential for an error-free mitosis. Kinetochore microtubule attachments that are too stable increase the rate of chromosome mis-segregation, a leading cause of chromosomal instability in tumors.

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Autori principali: Khodjakov, Alexey, Rieder, Conly L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891095/
https://ncbi.nlm.nih.gov/pubmed/19948139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.10.013
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