Role of astroglia in Down’s syndrome revealed by patient-derived human-induced pluripotent stem cells

Down’s syndrome (DS), caused by trisomy of human chromosome 21, is the most common genetic cause of intellectual disability. Here we use induced pluripotent stem cells (iPSCs) derived from DS patients to identify a role for astrocytes in DS pathogenesis. DS astroglia exhibit higher levels of reactiv...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Chen, Chen, Jiang, Peng, Xue, Haipeng, Peterson, Suzanne E., Tran, Ha T., McCann, Anna E., Parast, Mana M., Li, Shenglan, Pleasure, David E., Laurent, Louise C., Loring, Jeanne F., Liu, Ying, Deng, Wenbin
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109022/
https://ncbi.nlm.nih.gov/pubmed/25034944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5430
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars