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Genomic Instability in Pluripotent Stem Cells: Implications for Clinical Applications

Human pluripotent stem cells (hPSCs) are known to acquire genomic changes as they proliferate and differentiate. Despite concerns that these changes will compromise the safety of hPSC-derived cell therapy, there is currently scant evidence linking the known hPSC genomic abnormalities with malignancy...

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מידע ביבליוגרפי
Main Authors: Peterson, Suzanne E., Loring, Jeanne F.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931019/
https://ncbi.nlm.nih.gov/pubmed/24362040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R113.516419
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