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Colonic smooth muscle cells and colonic motility patterns as a target for irritable bowel syndrome therapy: mechanisms of action of otilonium bromide

Otilonium bromide (OB) is a spasmolytic compound of the family of quaternary ammonium derivatives and has been successfully used in the treatment of patients with irritable bowel syndrome (IBS) due to its specific pharmacodynamic effects on motility patterns in the human colon and the contractility...

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Autores principales: Rychter, Jakub, Espín, Francisco, Gallego, Diana, Vergara, Patri, Jiménez, Marcel, Clavé, Pere
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107708/
https://ncbi.nlm.nih.gov/pubmed/25057296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X14525250
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