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Colonic smooth muscle cells and colonic motility patterns as a target for irritable bowel syndrome therapy: mechanisms of action of otilonium bromide

Otilonium bromide (OB) is a spasmolytic compound of the family of quaternary ammonium derivatives and has been successfully used in the treatment of patients with irritable bowel syndrome (IBS) due to its specific pharmacodynamic effects on motility patterns in the human colon and the contractility...

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Main Authors: Rychter, Jakub, Espín, Francisco, Gallego, Diana, Vergara, Patri, Jiménez, Marcel, Clavé, Pere
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107708/
https://ncbi.nlm.nih.gov/pubmed/25057296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X14525250
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