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Efficacy of otilonium bromide in irritable bowel syndrome: a pooled analysis

BACKGROUND: Otilonium bromide (OB) is a spasmolytic agent acting as an L-type calcium channel antagonist in intestinal and colonic smooth muscle cells (SMCs). We analyzed three independent clinical trials with homogeneous design on patients with irritable bowel syndrome (IBS). After 2 weeks receivin...

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Bibliographic Details
Published in:Therap Adv Gastroenterol
Main Authors: Clavé, Pere, Tack, Jan
Format: Artigo
Language:Inglês
Published: SAGE Publications 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305018/
https://ncbi.nlm.nih.gov/pubmed/28246548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X16681708
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