Validation of a polygenic risk score for dementia in black and white individuals

OBJECTIVE: To determine whether a polygenic risk score for Alzheimer's disease (AD) predicts dementia probability and memory functioning in non-Hispanic black (NHB) and non-Hispanic white (NHW) participants from a sample not used in previous genome-wide association studies. METHODS: Non-Hispani...

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Autores principales: Marden, Jessica R, Walter, Stefan, Tchetgen Tchetgen, Eric J, Kawachi, Ichiro, Glymour, M Maria
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2014
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107377/
https://ncbi.nlm.nih.gov/pubmed/25328845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.248
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