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Mechanism underlying unaltered cortical inhibitory synaptic transmission in contrast with enhanced excitatory transmission in Ca(V)2.1 knockin migraine mice
Familial hemiplegic migraine type 1 (FHM1), a monogenic subtype of migraine with aura, is caused by gain-of-function mutations in Ca(V)2.1 (P/Q-type) calcium channels. In FHM1 knockin mice, excitatory neurotransmission at cortical pyramidal cell synapses is enhanced, but inhibitory neurotransmission...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Academic Press
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107271/ https://ncbi.nlm.nih.gov/pubmed/24907493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.05.035 |
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