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Alcoholics have more Tryptophan Hydroxylase 2 mRNA and Protein in the Dorsal and Median Raphe Nuclei
BACKGROUND: Chronic alcohol use depletes brain serotonin (5-HT), yet we previously found more tryptophan hydroxylase 2 (TPH2), the rate-limiting biosynthetic enzyme for 5-HT, in the dorsal raphe nucleus (DRN) of alcoholics. We sought to determine whether the increase in amount of TPH2 enzyme is asso...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107109/ https://ncbi.nlm.nih.gov/pubmed/24942188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12414 |
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