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Elevated expression of tryptophan hydroxylase-2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressed suicides

Deficient levels of serotonin are associated with suicide and depression. Paradoxically, in the dorsal raphe nucleus (DRN) there are more serotonin neurons and more neuronal tryptophan hydroxylase-2 (TPH2) expression postmortem in depressed suicides. In this study, we sought to determine whether gre...

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Detalhes bibliográficos
Main Authors: Bach-Mizrachi, H, Underwood, MD, Tin, A, Ellis, SP, Mann, JJ, Arango, V
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361383/
https://ncbi.nlm.nih.gov/pubmed/18180753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mp.4002143
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