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Elevated expression of tryptophan hydroxylase-2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressed suicides

Deficient levels of serotonin are associated with suicide and depression. Paradoxically, in the dorsal raphe nucleus (DRN) there are more serotonin neurons and more neuronal tryptophan hydroxylase-2 (TPH2) expression postmortem in depressed suicides. In this study, we sought to determine whether gre...

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Bibliografiske detaljer
Main Authors: Bach-Mizrachi, H, Underwood, MD, Tin, A, Ellis, SP, Mann, JJ, Arango, V
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361383/
https://ncbi.nlm.nih.gov/pubmed/18180753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mp.4002143
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