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Different oxysterols have opposing actions at N-methyl-D-aspartate receptors

Oxysterols have emerged as important biomarkers in disease and as signaling molecules. We recently showed that the oxysterol 24(S)-hydroxycholesterol, the major brain cholesterol metabolite, potently and selectively enhances NMDA receptor function at a site distinct from other modulators. Here we fu...

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Dettagli Bibliografici
Autori principali: Linsenbardt, Andrew J., Taylor, Amanda, Emnett, Christine M., Doherty, James J., Krishnan, Kathiresan, Covey, Douglas F., Paul, Steven M., Zorumski, Charles F., Mennerick, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107067/
https://ncbi.nlm.nih.gov/pubmed/24878244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.05.027
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