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Slow-pressor angiotensin II hypertension and concomitant dendritic NMDA receptor trafficking in estrogen receptor beta-containing neurons of the mouse hypothalamic paraventricular nucleus are sex and age dependent

The incidence of hypertension increases after menopause. Similar to humans, “slow-pressor” doses of angiotensin II (AngII) increase blood pressure in young males, but not in young female mice. However, AngII increases blood pressure in aged female mice, paralleling reproductive hormonal changes. The...

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Main Authors: Marques-Lopes, Jose, Van Kempen, Tracey, Waters, Elizabeth M., Pickel, Virginia M., Iadecola, Costantino, Milner, Teresa A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106979/
https://ncbi.nlm.nih.gov/pubmed/24639345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23569
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