Angiotensin II slow-pressor hypertension enhances NMDA currents and NOX2-dependent superoxide production in hypothalamic paraventricular neurons

Adaptive changes in glutamatergic signaling within the hypothalamic paraventricular nucleus (PVN) may play a role in the neurohumoral dysfunction underlying the hypertension induced by “slow-pressor” ANG II infusion. We hypothesized that these adaptive changes alter production of gp91(phox) NADPH ox...

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Autores principales: Wang, Gang, Coleman, Christal G., Chan, June, Faraco, Giuseppe, Marques-Lopes, Jose, Milner, Teresa A., Guruju, Mallikarjuna R., Anrather, Josef, Davisson, Robin L., Iadecola, Costantino, Pickel, Virginia M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
Materias:
Neural Control
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680791/
https://ncbi.nlm.nih.gov/pubmed/23576605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00367.2012
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