Repair of Oxidative DNA Base Damage in the Host Genome Influences the HIV Integration Site Sequence Preference

Host base excision repair (BER) proteins that repair oxidative damage enhance HIV infection. These proteins include the oxidative DNA damage glycosylases 8-oxo-guanine DNA glycosylase (OGG1) and mutY homolog (MYH) as well as DNA polymerase beta (Polβ). While deletion of oxidative BER genes leads to...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bennett, Geoffrey R., Peters, Ryan, Wang, Xiao-hong, Hanne, Jeungphill, Sobol, Robert W., Bundschuh, Ralf, Fishel, Richard, Yoder, Kristine E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106905/
https://ncbi.nlm.nih.gov/pubmed/25051054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103164
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados