The Base Excision Repair Pathway Is Required for Efficient Lentivirus Integration

An siRNA screen has identified several proteins throughout the base excision repair (BER) pathway of oxidative DNA damage as important for efficient HIV infection. The proteins identified included early repair factors such as the base damage recognition glycosylases OGG1 and MYH and the late repair...

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Bibliographic Details
Main Authors: Yoder, Kristine E., Espeseth, Amy, Wang, Xiao-hong, Fang, Qingming, Russo, Maria Teresa, Lloyd, R. Stephen, Hazuda, Daria, Sobol, Robert W., Fishel, Richard
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063173/
https://ncbi.nlm.nih.gov/pubmed/21448280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017862
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