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Quantitative Detection of 8-Oxo-7,8-dihydro-2′-deoxyguanosine Using Chemical Tagging and qPCR

[Image: see text] 8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGuo) is a commonly formed DNA lesion that is useful as a biomarker for oxidative stress. Although methods for selective quantification of 8-oxodGuo exist, there is room for additional methods that are sensitive and utilize instrumentation...

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Detalhes bibliográficos
Main Authors: Bajacan, John Ernest Vallarta, Hong, In Seok, Penning, Trevor W., Greenberg, Marc M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106692/
https://ncbi.nlm.nih.gov/pubmed/24932862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500120p
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