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Isocudraxanthone K Induces Growth Inhibition and Apoptosis in Oral Cancer Cells via Hypoxia Inducible Factor-1α

Isocudraxanthone K (IK) is a novel, natural compound from a methanol extract of the root bark of Cudrania tricuspidata. It has not been shown previously that IK possessed antitumor activity. We investigated the antitumor effects and molecular mechanism of IK and related signal transduction pathway(s...

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Detalhes bibliográficos
Main Authors: Shin, Mee-Ran, Lee, Hwa-Jeong, Kang, Soo-Kyung, Auh, Q-Schick, Lee, Young-Man, Kim, Youn-Chul, Kim, Eun-Cheol
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106071/
https://ncbi.nlm.nih.gov/pubmed/25105148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/934691
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