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Pokeweed antiviral protein alters splicing of HIV-1 RNAs, resulting in reduced virus production

Processing of HIV-1 transcripts results in three populations in the cytoplasm of infected cells: full-length RNA, singly spliced, and multiply spliced RNAs. Rev, regulator of virion expression, is an essential regulatory protein of HIV-1 required for transporting unspliced and singly spliced viral t...

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Detalhes bibliográficos
Main Authors: Zhabokritsky, Alice, Mansouri, Sheila, Hudak, Katalin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105749/
https://ncbi.nlm.nih.gov/pubmed/24951553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.043141.113
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