Association of hypometabolism and amyloid levels in aging, normal subjects

OBJECTIVE: We evaluated the relationship of amyloid, seen on Pittsburgh compound B (PiB)-PET, and metabolism, seen on [(18)F]-fluorodeoxyglucose (FDG)-PET, in normal subjects to better understand pathogenesis and biomarker selection in presymptomatic subjects. METHODS: Normal participants (aged 70–9...

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Main Authors: Lowe, Val J., Weigand, Stephen D., Senjem, Matthew L., Vemuri, Prashanthi, Jordan, Lennon, Kantarci, Kejal, Boeve, Bradley, Jack, Clifford R., Knopman, David, Petersen, Ronald C.
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105262/
https://ncbi.nlm.nih.gov/pubmed/24793183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000467
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